Both overweight and obesity are associated with an increased risk of CVD mortality1.
Obesity, especially abdominal obesity, increases the likelihood of developing diabetes, dyslipidemia, hypertension, CHD, stroke, and it has been clearly linked to poor health outcomes and all-cause mortality1,9.
An increase in the BMI is associated with adverse changes in the blood lipid profile resulting in elevated TC, LDL-cholesterol, and TG levels and low HDL-cholesterol levels10. The risk of comorbidities starts already with a BMI in the range of 25.0−29.9 Kg/m2 (overweight) and it further increases with a BMI greater than 30 Kg/m2 (obesity). Weight loss has a beneficial influence on HDL-cholesterol levels11 and also on TC and LDL-cholesterol in the long term12.
In this context, weight reduction in the presence of overweight, obesity and abdominal adiposity is recommended1,12 as it is associated with favorable effects on BP and dyslipidemia.
When present, excess intra-abdominal fat has been associated with several metabolic abnormalities, which may lead to CVD9. Assessing and monitoring changes in waist circumference over time may be helpful, in addition to measuring BMI, since it can provide an estimate of increased abdominal adiposity even in the absence of a change in BMI, thus screening for possible health risks13.