References

Anderson JW, Baird P, Davis RH, Jr. et al. Health benefits of dietary fiber. Nutr Rev 2009;67(4):188-205.

Appel LJ, Moore TJ, Obarzanek E et al. A clinical trial of the effects of dietary patterns on blood pressure. DASH Collaborative Research Group. N Engl J Med 1997;336:1117-24.

Benkhedda K, Boudrault C, Sinclair E et al Health Canada's Proposal to Accept a Health Claim about Soy Products and Cholesterol Lowering Food Risk Analysis Communication. International Food Risk Analysis Journal 2014, 4:22/doi10.5772/59411

Brindle P, Emberson J, Lampe F et al. Predictive accuracy of the Framingham coronary risk score in British men: prospective cohort study. BMJ 2003;327(7426):1267.

Carretero OA, Oparil S. Essential hypertension. Part I: definition and etiology. Circulation 2000;101(3):329-335.

Castro CM, de Vries JH, Van Oostrom AJ, Iestra J, van Staveren WA. Effects of a stanol-enriched diet on plasma cholesterol and triglycerides in patients treated with statins. J Am Diet Assoc 2006;106(10):1564-1569.

Catapano AL, Reiner Z, De Backer G et al. ESC/EAS Guidelines for the management of dyslipidaemias The Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS). Atherosclerosis 2011;217(1):3-46.

Centers for Disease Control and Prevention (US), National Center for Chronic Disease Prevention and Health Promotion (US), Office on Smoking and Health (US).Atlanta (GA). Centers for Disease Control and Prevention. How tobacco smoke causes disease: the biology and behavioural basis for smoking-attributable disease: a report of the surgeon general. 2010

Chiuve SE, McCullough ML, Sacks FM, Rimm EB. Healthy lifestyle factors in the primary prevention of coronary heart disease among men: benefits among users and nonusers of lipid-lowering and antihypertensive medications. Circulation 2006;114(2):160-167.

Commission Regualtion (EU) No 686/2014. Offcial Journal of the European Union 2014

D'Agostino RB, Vasan RS, Pencina MJ et al. General cardiovascular risk profile for use in primary care: the Framingham Heart Study. Circulation 2008;117(6):743-753.

de Souza RJ, Mente A, Maroleanu A et al. Intake of saturated and trans unsaturated fatty acids and risk of all cause mortality, cardiovascular disease, and type 2 diabetes: systematic review and meta-analysis of observational studies. BMJ 2015;351:h3978.

Despres JP. Body fat distribution and risk of cardiovascular disease: an update. Circulation 2012;126(10):1301-1313.

Eckel RH, Jakicic JM, Ard JD et al. 2013 AHA/ACC guideline on lifestyle management to reduce cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 2014;63(25 Pt B):2960-2984.

Eckel RH, Jakicic JM, Ard JD et al. 2013 AHA/ACC guideline on lifestyle management to reduce cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation 2014;129: S76-S99.

EFSA Panel on Dietetic Products NaAN. Scientific Opinion on Dietary Reference Values for fats, including saturated fatty acids, polyunsaturated fatty acids, monounsaturated fatty acids, trans fatty acids, and cholesterol. EFSA Journal 2010;8:1461 2010.

EFSA Panel on Dietetic Products NaAN. Scientific Opinion on Dietary References Values for carbohydrates and dietary fibre. EFSA Journal 2010;8(3):1462.

EFSA Panel on Dietetic Products Nutrition and Allergies (NDA). Scientific Opinion on Dietary Reference Values for protein. EFSA Journal 2012;10(2):2557.

EFSA Panel on Dietetic Products Nutrition and Allergies (NDA). Scientific Opinion on the Substantiation of a Health Claim Related to Soy Protein and Reduction of Blood Cholesterol Concentrations Pursuant to Article 14 of the Regulation (EC) no 1924/2006. EFSA Journal 2010;8(1688).

Estruch R, Ros E, Salas-Salvado J et al. Primary prevention of cardiovascular disease with a Mediterranean diet. N Engl J Med 2013;368(14):1279-1290.

European Society of Cardiology. European Cardiovascular Disease Statistics. 2012 http://www.escardio.org/The-ESC/Initiatives/EuroHeart/2012-European-Cardiovascular-Disease-Statistics

Ference BA, Yoo W, Alesh I et al. Effect of long-term exposure to lower low-density lipoprotein cholesterol beginning early in life on the risk of coronary heart disease: a Mendelian randomization analysis. J Am Coll Cardiol 2012;60(25):2631-2639.

Freeland-Graves JH, Nitzke S. Position of the academy of nutrition and dietetics: total diet approach to healthy eating. J Acad Nutr Diet 2013;113(2):307-317.

Gylling H, Plat J, Turley S et al. Plant sterols and plant stanols in the management of dyslipidaemia and prevention of cardiovascular disease. Atherosclerosis 2014;232(2):346-360.

Hecker KD, Kris-Etherton PM, Zhao G, Coval S, St JS. Impact of body weight and weight loss on cardiovascular risk factors. Curr Atheroscler Rep 1999;1(3):236-242.

How tobacco Smoke Causes Disease: The Biology and Behavioral Basis for Smoking-Attributable diseaseliana. A Report of the Surgeon General. 2010

Jakulj L, Trip MD, Sudhop T, von BK, Kastelein JJ, Vissers MN. Inhibition of cholesterol absorption by the combination of dietary plant sterols and ezetimibe: effects on plasma lipid levels. J Lipid Res 2005;46(12):2692-2698.

Jarcho JA, Keaney JF, Jr. Proof That Lower Is Better--LDL Cholesterol and IMPROVE-IT. N Engl J Med 2015;372(25):2448-2450.

Jenkins DJ, Jones PJ, Lamarche B et al. Effect of a dietary portfolio of cholesterol-lowering foods given at 2 levels of intensity of dietary advice on serum lipids in hyperlipidemia: a randomized controlled trial. JAMA 2011;306(8):831-839.

Jenkins DJ, Kendall CW, Faulkner D et al. A dietary portfolio approach to cholesterol reduction: combined effects of plant sterols, vegetable proteins, and viscous fibers in hypercholesterolemia. Metabolism 2002;51(12):1596-1604.

Jenkins DJ, Kendall CW, Faulkner DA et al. Assessment of the longer-term effects of a dietary portfolio of cholesterol-lowering foods in hypercholesterolemia. Am J Clin Nutr 2006;83(3):582-591.

Jenkins DJ, Kendall CW, Faulkner DA et al. Long-term effects of a plant-based dietary portfolio of cholesterol-lowering foods on blood pressure. Eur J Clin Nutr 2008;62(6):781-788.

Jensen MD, Ryan DH, Apovian CM et al. 2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society. Circulation 2014;129(25 Suppl 2):S102-S138.

Joint British Societies' consensus recommendations for the prevention of cardiovascular disease (JBS3). Heart 2014;100 Suppl 2:ii1-ii67.

Klatsky AL. Alcohol and cardiovascular health. Physiol Behav 2010;100(1):76-81.

Kromhout D, Yasuda S, Geleijnse JM, Shimokawa H. Fish oil and omega-3 fatty acids in cardiovascular disease: do they really work? Eur Heart J 2012;33(4):436-443.

Lamon-Fava S, Wilson PW, Schaefer EJ. Impact of body mass index on coronary heart disease risk factors in men and women. The Framingham Offspring Study. Arterioscler Thromb Vasc Biol 1996;16(12):1509-1515.

Li Y, Hruby A, Bernstein AM et al. Saturated Fats Compared With Unsaturated Fats and Sources of Carbohydrates in Relation to Risk of Coronary Heart Disease: A Prospective Cohort Study. J Am Coll Cardiol 2015;66(14):1538-1548.

Lin X, Racette SB, Lefevre M et al. Combined effects of ezetimibe and phytosterols on cholesterol metabolism: a randomized, controlled feeding study in humans. Circulation 2011;124(5):596-601.

Mancia G, Fagard R, Narkiewicz K et al. 2013 ESH/ESC guidelines for the management of arterial hypertension: the Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Eur Heart J 2013;34(28):2159-2219.

Mannu GS, Zaman MJ, Gupta A, Rehman HU, Myint PK. Evidence of lifestyle modification in the management of hypercholesterolemia. Curr Cardiol Rev 2013;9(1):2-14.

Mensink RP, Ebbing S, Lindhout M, Plat J, van Heugten MM. Effects of plant stanol esters supplied in low-fat yoghurt on serum lipids and lipoproteins, non-cholesterol sterols and fat soluble antioxidant concentrations. Atherosclerosis 2002;160(1):205-213.

Mensink RP, Zock PL, Kester AD, Katan MB. Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a meta-analysis of 60 controlled trials. Am J Clin Nutr 2003;77(5):1146-1155.

Messina M. Insights gained from 20 years of soy research. J Nutr 2010;140(12):2289S-2295S.

Mozaffarian D, Aro A, Willett WC. Health effects of trans-fatty acids: experimental and observational evidence. Eur J Clin Nutr 2009;63 Suppl 2:S5-21.

Mozaffarian D, Wu JH. Omega-3 fatty acids and cardiovascular disease: effects on risk factors, molecular pathways, and clinical events. J Am Coll Cardiol 2011;58(20):2047-2067.

Neil HA, Meijer GW, Roe LS. Randomised controlled trial of use by hypercholesterolaemic patients of a vegetable oil sterol-enriched fat spread. Atherosclerosis 2001;156(2):329-337.

Nordic Nutrition Recommendations 2012. Integrating nutrition and physical activity. https://www.norden.org/en/theme/nordic-nutrition-recommendation/nordic-nutrition-recommendations-2012.

Normen L, Bryngelsson S, Johnsson M et al. The phytosterol content of some cereal foods commonly consumed in Sweden and in Netherlands. Journal of Food Composition and Analysis 2002; 15: 693-704.

Normen L, Ellgard L, Brants H, Dutta P, Andersson H. A phytosterol database: Fatty foods consumed in Sweden and the Netherlands. Journal of Food Composition and Analysis 2007; 20: 193-201.

Normen L, Johnsson M, Andersson H, van Gamerson Y, Dutta P. Plant sterols in vegetables and fruits commonly consumed in Sweden. Eur J Nutr 1999;38(2):84-89.

Obarzanek E, Sacks FM, Vollmer WM et al. Effects on blood lipids of a blood pressure-lowering diet: the Dietary Approaches to Stop Hypertension (DASH) Trial. The American journal of clinical nutrition 2001;74:80-9.

O'Keefe JH, Bybee KA, Lavie CJ. Alcohol and cardiovascular health: the razor-sharp double-edged sword. J Am Coll Cardiol 2007;50(11):1009-1014.

Perk J, De Backer G, Gohlke H et al. European Guidelines on cardiovascular disease prevention in clinical practice (version 2012). The Fifth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of nine societies and by invited experts). Eur Heart J 2012;33(13):1635-1701.

Piironen V, Toivo J, Lampi AM. Natural Sources of Dietary Plant Sterols.. Natural Sources of Dietary Plant Sterols. Journal of Food Composition and Analysis 2000; 13: 619-624.

Ras RT, Geleijnse JM, Trautwein EA. LDL-cholesterol-lowering effect of plant sterols and stanols across different dose ranges: a meta-analysis of randomised controlled studies. Br J Nutr 2014;112(2):214-219.

Reiner Z, Catapano AL, De Backer G et al. ESC/EAS Guidelines for the management of dyslipidaemias: the Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS). Eur Heart J 2011;32(14):1769-1818.

Robinson JG, Smith B, Maheshwari N, Schrott H. Pleiotropic effects of statins: benefit beyond cholesterol reduction? A meta-regression analysis. J Am Coll Cardiol 2005;46(10):1855-1862.

Sabate J, Oda K, Ros E. Nut consumption and blood lipid levels: a pooled analysis of 25 intervention trials. Arch Intern Med 2010;170(9):821-827.

Sabate J, Wien M. Nuts, blood lipids and cardiovascular disease. Asia Pac J Clin Nutr 2010;19(1):131-136.

Sacks FM, Appel LJ, Moore TJ et al. A dietary approach to prevent hypertension: a review of the Dietary Approaches to Stop Hypertension (DASH) Study. Clinical Cardiology 1999;22:III6-10.

Sacks FM, Lichtenstein A, Van HL, Harris W, Kris-Etherton P, Winston M. Soy protein, isoflavones, and cardiovascular health: an American Heart Association Science Advisory for professionals from the Nutrition Committee. Circulation 2006;113(7):1034-1044.

Shen J, Wilmot KA, Ghasemzadeh N et al. Mediterranean Dietary Patterns and Cardiovascular Health. Annu Rev Nutr 2015;35:425-449.

Siervo M, Lara J, Chowdhury S, Ashor A, Oggioni C, Mathers JC. Effects of the Dietary Approach to Stop Hypertension (DASH) diet on cardiovascular risk factors: a systematic review and meta-analysis. Br J Nutr 2014;1-15.

Siri-Tarino PW, Sun Q, Hu FB, Krauss RM. Saturated fatty acids and risk of coronary heart disease: modulation by replacement nutrients. Curr Atheroscler Rep 2010;12(6):384-390.

Slavin J. Why whole grains are protective: biological mechanisms. Proc Nutr Soc 2003;62(1):129-134.

Sofi F, Abbate R, Gensini GF, Casini A. Accruing evidence on benefits of adherence to the Mediterranean diet on health: an updated systematic review and meta-analysis. Am J Clin Nutr 2010;92(5):1189-1196.

Stroes ES, Thompson PD, Corsini A et al. Statin-associated muscle symptoms: impact on statin therapy-European Atherosclerosis Society Consensus Panel Statement on Assessment, Aetiology and Management. Eur Heart J 2015;36(17):1012-1022.

Taku K, Umegaki K, Sato Y, Taki Y, Endoh K, Watanabe S. Soy isoflavones lower serum total and LDL cholesterol in humans: a meta-analysis of 11 randomized controlled trials. Am J Clin Nutr 2007;85(4):1148-1156.

The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III). Final Report 2002

Theuwissen E, Mensink RP. Water-soluble dietary fibers and cardiovascular disease. Physiol Behav 2008;94(2):285-292.

United States Department of Agriculture Agricultural Research Service. National Nutrient Database for Standard Reference Release 27. 2015.

Vafeiadou K, Weech M, Altowaijri H et al. Replacement of saturated with unsaturated fats had no impact on vascular function but beneficial effects on lipid biomarkers, E-selectin, and blood pressure: results from the randomized, controlled Dietary Intervention and VAScular function (DIVAS) study. Am J Clin Nutr 2015;102(1):40-48.

Valsta LM, Lemstrom A, Ovaskainen ML et al. Estimation of plant sterol and cholesterol intake in Finland: quality of new values and their effect on intake. Br J Nutr 2004;92(4):671-678.

Vannice G, Rasmussen H. Position of the academy of nutrition and dietetics: dietary fatty acids for healthy adults. J Acad Nutr Diet 2014;114(1):136-153.

Warren TY, Barry V, Hooker SP, Sui X, Church TS, Blair SN. Sedentary behaviors increase risk of cardiovascular disease mortality in men. Med Sci Sports Exerc 2010;42(5):879-885.

Weggemans RM, Zock PL, Katan MB. Dietary cholesterol from eggs increases the ratio of total cholesterol to high-density lipoprotein cholesterol in humans: a meta-analysis. Am J Clin Nutr 2001; May;735(5):885-891.

Whitehead A, Beck EJ, Tosh S, Wolever TM. Cholesterol-lowering effects of oat beta-glucan: a meta-analysis of randomized controlled trials. Am J Clin Nutr 2014;100(6):1413-1421.

Wiegman A, Gidding SS, Watts GF, Chapman MJ, Ginsberg HN et al. Familial Hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatmentEur Heart J. 2015 Sep 21;36(36):2425-37.

Williams KJ, Feig JE, Fisher EA. Rapid regression of atherosclerosis: insights from the clinical and experimental literature. Nat Clin Pract Cardiovasc Med 2008;5(2):91-102.

World Health Organization. Global Recommendations on Physical Activity for Health. WHO Guidelines Approved by the Guidelines Review Committee 2010.

World Health Organization. Global status report on noncommunicable diseases 2014. 2014

World Health Organization. Regional estimates for 2000-2012. http://www.who.int/ healthinfo/global_burden_disease/estimates_regional/en/index1.html

Zampelas A. From the Maastricht meeting to the European Atherosclerosis Society Consensus on phytosterols/phytostanols: what is new of an old story? Atherosclerosis 2014;233(2):357-358.

Zhou D, Yu H, He F et al. Nut consumption in relation to cardiovascular disease risk and type 2 diabetes: a systematic review and meta-analysis of prospective studies. Am J Clin Nutr 2014;100(1):270-277.

Zhu X, Sun X, Wang M et al. Quantitative assessment of the effects of beta-glucan consumption on serum lipid profile and glucose level in hypercholesterolemic subjects. Nutr Metab Cardiovasc Dis 2015;25(8):714-723.